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De Quervain's tendinosis occurs when the tendons around the base of the thumb are irritated or constricted and swell.  

The main symptom of De Quervain's tendinosis is pain felt over the thumb side of the wrist and can travel up the forearm. The pain may appear either gradually or suddenly. The pain is usually worse when the hand and thumb are in use and when grasping objects or twisting the wrist.  You may also see swelling over the thumb side of the wrist and you may experience a 'catching' or 'snapping' sensation when moving your thumb.  Ultimately the pain and swelling may make it difficult to move the thumb and wrist.

Treatment

The aim to treating De Quervain's tendinosis is to relieve the pain caused by irritation and swelling.  Splints may be used to rest the thumb and wrist and your surgeon may prescribe anti-inflammatory medication.   Your surgeon may suggest a steroid injection of corticosteroids into the tendon sheath to help reduce swelling and pain.

Ultimately if non-surgical treatment does not work your surgeon can perform a De Quervain's release.